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Volume 3 (2024)

Short Report

Stent-Assisted Coil Embolization of MCA Bifurcation and Literature Review

Xiao-Dong Wang*

Coil embolization of aneurysms, after more than 20 years of clinical practice shows that several conditions must be met: 1. After the necessary interval, the entire aneurysm can achieve and maintain effective hemostasis.

Case Report

A Case Study of Comorbid Psychogenic Non-Epileptic Seizures and Epileptic Seizures in an Adolescent Female with Depression

He Yangliuqing; Liang Fenrong; Wang Yiming*; Wei Yuhan; Ma Tianpei

Among patients with Psychogenic Non-Epileptic Seizures (PNES), about 10% to 30% have epilepsy, which brings some difficulties in diagnosis. Usually, psychogenic non-epileptic seizures and epileptic seizures occur independently at different points in time, and their performance is similar, but rarely seizures can occur several times in a row.

Review Article

Counseling for Diabetes

Michael F Shaughnessy*; James Devlin

Individuals who have been diagnosed with either Type I or Type II diabetes face a number of emotional challenge. Children and adolescents are faced with self-monitoring and trips to the local physician and adults are faced with dietary and self-medication challenges. This paper explores some of the issues faced by counselors who work with children/adolescents and adults with diabetes.

Research Article

Photoluminescence of L-Valine Irradiated with Small Doses

Yu А Bandurin*; Yu V Fedurtsja; А V Rusin; Sh B Molnar; О Yu Bandurin

The measurement technique and the results obtained by optical spectroscopy during excitation of L-valine molecules by photons described. The photoluminescence spectra of L-valine studied in the wavelength range 400-700 nm during excitation by photons of different energies 3.26-4.51 eV.

Review Article

Investigating Microbial Dynamics and Bacterial Vaginosis Susceptibility in Women who have Sex with Women

Julia Vinagolu-Baur; Kelly Frasier; Vivian Li; Darianne Zimmer; Abigail Zimmer; Michelle Sobotka

Bacterial Vaginosis (BV) remains a prevalent gynecologic health concern, with emerging research indicating a potential association between women who have sex with women (WSW) and an increased susceptibility to BV infections.

Case Report

Hemophagocytic Lymphohistiocytosis Triggered by COVID-19: A Case Report and Literature Review

Yuexia Zhang; Qian Zhang; Xuan Wang; Rui Song; Jiaofeng Bai; Ruirui Zheng; Zhichen Zhang; Bianli Lian; Yaozhu Pan*

Hemophagocytic Lymphohistiocytosis (HLH) is a rare life-threatening inflammatory response syndrome associated with immune deregulation, which is prone to misdiagnosis due to the lack of specificity of clinical symptoms, leading to poor prognosis. COVID-19 is an acute respiratory disease with high infectiousness caused by the novel coronavirus SARS-CoV-2.

Research Article

Alzheimer's Disease Treatment with Chronic Antiorthostatic Sleeping in -4o to -50o, Periodic and Progressive Conditions, Blood Shift to the Head and Simulated Microgravity

Alexei B Fedorov; Sergei K Denogratov; Nikolai C Neofitov*; Pavel L Merkov

Chronic antiorthostatic sleeping (CAS) in -40 to -500 involves Periodic and Progressive Conditions (PPC), Blood Shift to the Head (BSH) and simulated microgravity (SMG) and blood boosts to the brain. We hypothesized that CAS could treat Alzheimer's disease. We sought to determine the extent to which CAS could treat Alzheimer's.

Research Article

Centralized Medical Observation in the COVID-19 Response: A Retrospective Field Study

Jian Jiang*; Wenqing Rao; Xuwei Tang; Xiangju Hu; Shuting Wu

Non-drug interventions are the most active and effective response strategies until the availability of 100% effective vaccines and antiviral drugs. As one of the important means of non-drug interventions, centralized medical observation plays a crucial role in the epidemic prevention and control.

Short Commentary

The Role of Five Classical Signs of Inflammation in the Pathogenesis and Clinical Picture of Acute Pneumonia

Igor Klepikov*

The modern understanding of of the acute inflammatory process of the lungs is based on the characteristics of pathogens, the aggressive properties of which modern medicine has been trying for many years to explain the severity and nuances of clinical manifestations, and their effective neutralization is presented as the main and in fact the only way to achieve a therapeutic effect.

Clinical Image

Skull Shape Traumatic White Cataract

Houda Brarou*; Manal Bouggar; Zakaria Chaabi; Soundouss Sebbata; Lucrece Joannele Eriga Vydalie; Soukaina Laaouina; Samah Sadiki; Nermine Belayachi; Taoufik Abdellaoui; Yassine Mouzari; Abdelbarre Oubaaz

A 32 years old male patient presented to the Ophthalmology Department reporting a progressive decrease in vision in his right eye (OD) in the past year. He reported a history of blunt right eye injury while 18 months ago. At the time of the injury, the patient was asymptomatic. After the incident occurred, the patient did not have a further ophthalmic examination.

Clinical Image

Blue-Green Inclusions in Neutrophils in a Patient with Pancreatic Necrosis

Tatiyana V Konyuhova; Ekaterina V Trukhina*

Blue-green cytoplasmic inclusions in neutrophils in peripheral blood smears are an important finding described in critically ill patients and associated mainly with acute liver failure and lactic acidosis. Also, blue-green inclusions have been described in patients with multiple organ failure, COVID19 infection, yellow fever and sepsis caused by E. Coli.

Short Commentary

A Critical Assessment of Inpatient Dermatology Service Line in the Rural United States

Anna Conner*; Nupur Singh; Zachary Nahmias

Dermatological services in rural America are sparse, and minimal research is published on the demographics and presentations of patients and their dermatologic conditions in these areas. There are 3.4 dermatologists per 100,000 people in the United States (U.S.); while this density has increased in the past two decades, it is less than the recommended 4 per 100,000 [1].

Research Article

Aging is Another Word for Living: Health-Related Quality of Life Among Elderly - A Review

Suja Kumari S*; Renjulal Yasodharan

The pandemic 2019 coronavirus illness (COVID-19), which caused massive mortality, spread quickly across continents. Older persons are more vulnerable to COVID-19 infection, particularly those with medical conditions.

Short Commentary

Botanical, Chemical, and Pharmacological Characteristics of Carob Tree (Ceratonia Siliqua L)

Rahal El Kahkahi*; Meryama Moustaine; Rachid Zouhair

In Morocco the carob tree (Ceratonia siliqua L.), is scattered in the wild or articificial state throughout the country. It belongs to the Ceasalpiniaceae subfamily of the legume family, is a sclerophyllous, xerophilic, thermophilic, calciclous and heliophilous species.

Research Article

Machine Learning-Based Feature Selection for Predicting Autism Spectrum Disorder in Pediatric Neurodevelopmental Disorders

Maryam Asadinezhad; Leila Pazouki; Zahra Mahmoodkhani; Negareh Poursalehi; Aria Jahanimoghadam; Maryam Moradnia; Mohammad Yahya Vahidi Mehrjardi*; Mojtaba Movahedinia*

In this study, we aimed to utilize machine learning techniques to facilitate the early detection of autism in children, with the understanding that early intervention can significantly improve treatment outcomes and enhance self-sufficiency in adult life. Our research focused on 125 samples obtained from clinics in Yazd, Iran.

Case Report

Catamenial Anaphylaxis: A Case Report with Cyclical Issue

Mohammad Hassan Bemanian; Mina Ahmadi*; Fatemeh Afrashteh

Catamenial anaphylaxis, a scarcity subtype of menstrual cycle-associated allergic reactions, characterized by a spectrum of manifestations ranging from mild cough or the severe angioedema and loss of consciousness due to hypersensitivity reactions occurring predominantly during the first days of menstruation.

Research Article

Water, Sanitation and Hygiene Services in Healthcare Facilities in Bayelsa State Nigeria: A Primordial Prevention Strategy for Infectious Disease Control

Priscilla Chidinma Ogbonna*; Evangeline T Oparaocha; Evangel Chinyere Anyanwu

Lack or inadequate Water, Sanitation and Hygiene (WASH) in Healthcare Facilities (HCF) have been reported severally as having an impact on the transmission of infectious diseases or outbreak of infectious diseases in a healthcare setting.

Short Commentary

Dentogenic Blockages of the Glymphatic System and the Resulting Brain Problems

Doepp Manfred*

The brain has a glymphatic system for detoxification, which drains the toxins into the lymphatic system of the head. This system is stressed by toxin-producing processes in the mouth area to the point of blockage.

Research Article

Abnormal Changes of Cerebral Blood Flow in Hypertension with Different Risk Levels

Baijie Wang#; Ge Zhang#; Xiuchun Wang; Chunyan Yu; Qiang Li; Weizhao Lu; Feng Wang*; Yan Shao*

The purpose of this study was to examine the different alterations in Cerebral Blood Flow (CBF) induced by hypertension across various risk levels.


Research Article

Predictive Value of Six-Minute Walking Test in Post-Acute Myocardial Infarction Patients in Benghazi

Essam A Eldenna; Faiza A Elhamdy; Nagwa Elghryani*; Mohamed M Khamis

Acute Myocardial Infarction (AMI) poses a significant threat to heart health. The six-Minute Walking Test (6MWT) assesses patients' ability to walk the longest distance possible on a level course in six minutes, with parameters like arterial pressure, heart rate, and oxygen saturation monitored.


Research Article

Seroprevalence and Associated Factors of Ovine and Caprine Brucellosis in Dubti District of Afar Region, Ethiopia

Teshager Dubie*; Trhas Kasa; Getachew Kinfe*

Brucellosis is a bacterial zoonotic disease that causes reproductive losses in animals and poses public health hazards as well as economic impact in sub-Saharan Africa including Ethiopia.


Research Article

Deciphering the Causal Relationships between Blood Metabolites and Coronary Atherosclerosis: A Comprehensive Mendelian Randomization Study

Song Liantai; Zhao Yujia; Tian Feng; Yang Mengxin; Zhang Wenhui; Wu Jianzhao; Li Rong; Xu Qian*

This study aims to investigate the causal relationships between specific blood metabolites and the risk of coronary atherosclerosis using a two-sample Mendelian Randomization (MR) approach.


Research Article

Investigation of Clock Genes Expression in G-CSF Mobilized Individuals at Different Hours of the Day

Sanaz Aghajani; Alireza Farsinejad; Elham Roshandel; Abbas Hajifathali*

Studies have shown that the mobilization of Hematopoietic Stem Cells (HSCs) is continuous and dependent on the circadian rhythms. In this study we have aimed to investigate of clock genes including PER-1, PER-2, PER-3 and CRY-1 expression in G-CSF-mobilized individuals at different hours of the day.


Research Article

Prevalence, Types, Risk Factors, and Outcome of Congenital Malformations in Two Health Facilities in the South West Region of Cameroon

Yolande Djike PF*; Charlotte Eposse; Winifred N Abanda; Yanelle Wandji; Diomède N Njinkui; Naiza Monono; Godlove K Jator; Andreas Chiabi

Birth defects also known as congenital abnormalities are structural or functional anomalies that occur during intrauterine life and can be identified prenatally, at birth, or be detected later in infancy.


Research Article

Chailing Decoction Generated Foxp3+ Regulatory T Cells and Suppressed Activity of mTOR Signaling Pathway in a Murine Cardiac Transplantation Model

Deli Cui; Youman Zhang; Changjun Tan; Zhong Liu*

To investigate the effects of Chailing Decoction, a herbal medicine, on the generation of regulatory T cells (Tregs) and its potential signaling pathways in preventing graft rejection. Methods: The study utilized C3H mice that underwent cardiac transplantation and received either Chailing Decoction or rapamycin.


Short Report

Vulvar Angiokeratoma after Radical Hysterectomy and Radiotherapy: Case Report

Hamraoui Hafsa*; Elloudi Sara; Baybaye Hanane; Soughi Meryem; Douhi Zakia; Mernissi Fatima Zahra

Angiokeratomas are relatively rare vascular malformations, whose surface is keratotic and located at the vulvar level called Fordyce angiokeratoma. We report the case of a vulvar angiokeratoma post hysterectomy and radiotherapy.


Research Article

Factors Associated with the Satisfaction of Parents of Children Hospitalized in the Pediatric Ward in Togo

Takassi Ounoo Elom*; Agbeko Foli ; Djadou Koffi Edem

Patient satisfaction is a central element in the evaluation of the quality of care. The objective of the study was to describe the factors associated with the satisfaction of parents of children hospitalized in the pediatric ward at the Sylvanus Olympio Teaching Hospital.


Review Article

Insect Chemosensory Proteins against COVID-19

Jean-François Picimbon*

This article describes a novel strategy to fight SARS-CoV-2 infection by employing tiny soluble binding proteins called "Odorant Binding Proteins" (OBPs), "Niemann-Pick Type C2 (NPC2s)"


Case Report

New Cardiovascular Event One Year Later in Patient with Good Control of Cardiovascular Risk Factor

Domenico Mario Giamundo*; Francesco Barillà; Lucy Barone; Alessio Di Landro; Domenico Sergi; Massimo Marchei

Secondary prevention after SCA (Acute Coronary Syndrome) is of paramount importance to reduce the incidence of MACE and improve prognosis in follow-up. The control of avoidable risk factors.


Research Article

Pediatric Atelectasis: Insights from Diagnostic Imaging

Rebeca Tenajas; David Miraut*

This article presents a detailed case study of a 10-year-old child, born in 2013, exhibiting symptoms of a febrile syndrome and subsequent diagnostic findings suggestive of atelectasis through chest radiography and Computed Tomography (CT) scans without intravenous contrast


Research Article

Patterns and Determinants of Undernutrition in Pre-School Age Children in the North West Region of Cameroon

Andreas Chiabi*; Rosine Ngum; Loveline Lum Niba; Alex Tatang Mambap; Samuel Angwafor; Gloria Ashuntantang

Malnutrition is a major public health concern for children under five years. About 45% of deaths among children under five years globally are linked to undernutrition.


Research Article

Evaluation of the Antimicrobial and Antioxidant Activity of the Pulp of Artocarpus Heterophyllus Lam (Moraceae)

Johnson-Ajinwo*; Okiemute Rosa*; Paul-Worika; Priscilla Nengi

Artocarpus heterophyllus Lam. (Moraceae) - Jackfruit beyond its culinary uses has been used to treat ailments ethnomedicinally. Its bark, leaves, seeds, and pulp are rich sources of bioactive compounds.


Research Article

Digital Twins for Risk Prediction of Microwave Radiation in the Human Eye

Adamopoulou Maria; Makrynioti Dimitra; Fouras Athanasios; Messaris Gerasimos; Hatzilygeroudis Ioannis; Koutsojannis Constantinos*

Recent studies support the long-held belief that the lens of the eye is one of the human body's most radiosensitive tissues, especially in the ocular region. This study highlights the influence of non-ionizing electromagnetic radiation, which may cause cataracts or other visual illnesses.


Short Commentary

Italian Spetiale/Medical Doctor in the 17th/18th Century: Culture, Food and Environment or a Better Healthness

Pierfrancesco Morganti*; Pier Paolo Visentin; Hong-Duo Chen

The way of thinking and working of the ancient pharmacists and medical doctors have been repored together with some "curious" prescriptions, comparing and focusing their culture to the actual way of living.


Research Article

Selenium and Atherosclerosis: A Case-Control Study in a Hospital in Izmir

Cagla Yuksek*; Raika Durusoy; Necmeddin Yakut; Isil Ergin

Atherosclerosis is an arterial disease with thickening of the vessel wall and loss of flexibility. The mostly accepted hypothesis about its pathogenesis is oxidative stress. Selenium is an essential element protecting against oxidative damage.


Research Article

Clinical and Polysomnographic Profile of Patients with Sleep Disordered Breathing in a Tertiary Care Hospital

Shashibhushan BL; Aditya Shashibhushan*; Ashwin K

Obstructive Sleep Apnea (OSA) is a prevalent sleep disorder associated with various health complications, yet it often remains undiagnosed. Understanding its clinical and polysomnographic profiles is crucial for effective management.


Short Report

High Intercostal Space Twelve-Lead ECG in Arrhythmogenic Cardiomyopathy

Stefan Peters*

The value of high intercostal spaces of lead V1 and V2 is analyzed in arrhythmogenic cardiomyopathy. In this ECG writing technique a localized right precorial QRS prolongation and right precordial T-wave inversion can be demonstrated. In normal intercostal spaces only electroanatomic scar and myocardial atrophy documented in lead aVR was present.


Short Commentary

Typical Electrocardiographic Features in Arrhythmogenic Left Ventricular Cardiomyopathy

Stefan Peters*

Since 2020 arrhythmogenic cardiomyopathy includes a right dominant form, a biventricular form and a left dominant form. Already in 2004 Carvajal syndrome was first described in Ecuador within families [1]. This syndrome includes a slighty dilated, poor contracting left ventricle and hair and skin abnormalities with curly hair and plantopalmar keratosis. The genetic background were mutations of the desmoplakin gene.


Review Article

Trends in the Application of Stem Cells for the Treatment of Diabetes

Jember Tesfahun Bekele*; Gizaw Solomon Tebeje

Diabetes mellitus is a global epidemic that showed a dramatic worldwide increase in its incidence and has been associated with life threatening complications if not detected and managed properly. Even though, insulin and oral anti-diabetic drugs were used for its management, lots of efforts are made to improve patient's care by pancreas and islet transplantation along with stem cell therapies like embryonic stem cells, induced pluripotent stem cells and adult mesenchymal stem cells.


Research Article

Prevalence of Diseases in Internally Displaced Persons Camps during Climate Change (Flooding) in a Low-Income Setting

Chuma Edward Emembolu; Ben Afam Obidike; Ijeoma Valentina Ikeanyionwu; Afam Cyril Anaeme; Caroline Onyeari Njaka; Kenneth Uzoechina Nwokolo; Nonye Juliana Ezeonyejiaku; Chinenye John Peter Obi; Arinze Anthony Onwuegbuna; Onyeka Chukwudalu Ekwebene; Johnbosco Emmanuel Mamah; George Uchenna Eleje*

To determine the common diseases in the Internally Displaced Persons (IDPs) camps during the flooding. The study was conducted in IDP camps in Anambra State, south-east Nigeria during the last quarter of 2022 (October to December 2022). Secondary data obtained from patients' record booklets was used. A total number of 19,080 people were in the camps.


Short Commentary

Αnxiety, Depression and Stress in People Undergoing Surgery

Theofilidis Antonios*; Paramythiotis Daniel; Michalopoulos Antonios

The burden of negative emotional states, such as anxiety and depression and stress in people undergoing surgery it is indisputable, because it is a critical event that often happens perceived as an unfamiliar and frightening experience.


Clinical Image

A Case of Lymphoplasmacytic Cell Lymphoma Characterized by Marked Nuclear Fission and Brain Gyrus Nuclei of Lymphocytes

Zailin Yang; Yu Peng; Longrong Ran; Xuelian Wu; Shuang Chen*

A 67-year-old male was admitted to the hospital due to fatigue and thrombocytopenia. Peripheral blood cells analysis showed the white blood cells count of 2.99 × 109/L, red blood cell (RBC) count of 2.08 × 1012/L, platelet count


Clinical Image

A Case of Dysphagia due to an Esophageal Duplication Cyst in a Difficult Anatomical Site: A Challenging Situation for Endoscopic Treatment

Christos Sotiropoulos*; Christos Konstantakis; Odysseas Ampazis; Georgia Diamantopoulou, Georgios Theocharis; Christos Triantos; Konstantinos Thomopoulos

Esophageal duplication cyst is a rare congenital cyst that results from aberration of the posterior division of the embryonic foregut at the fourth to eighth week of gestation. Most of these cysts become symptomatic in childhood, whereas in adults they are usually an asymptomatic incidental radiographic or endoscopic finding.


Review Article

Critical Analysis of Health Literacy and its Impact on Health Outcomes

Olufemi Segun Shoyemi*; Abdulsalam A; Iyabo Funmilayo Dorcas Oni; Abubakar Ibrahim Hassan; Azeez TA

Health literacy has to do with the individual's capacity to understand, access and apply information available to health so as to make better choices and decisions. In recent times, the increased numbers of health illiterate across the globe with many having difficulties in grasping the notion of disease prevention and several struggling with health promotion.


Review Article

Reticulocyte Indexes and their Significance

Bashir Abdrhman*

A crucial diagnostic tool for assessing, categorizing, and monitoring the effectiveness of anemia treatment is the reticulocyte count. The quality of erythropoiesis is an intrinsic aspect of the pathophysiology of anemia, and the ability of reticulocyte production would be one of the pivotal factors in the quality of erythropoiesis.


Review Article

Examination of the Effectiveness of Health Education Programs in Preventing Chronic Diseases

Olufemi Segun Shoyemi*; Abdulsalam A; Iyabo Funmilayo Dorcas Oni; Abubakar Ibrahim Hassan; Taye Oladele ARO; Azeez TA

Chronic diseases such as cancer, cardiovascular diseases, metabolic dysfunctions, infectious diseases, HIV and other noncommunicable diseases continue to account for increased rate of mortality.


Research Article

Folic Acid in Neuropsychiatric Disorders

Leonardo Massoni*

It is known that Folic Acid (FA) plays an important role in normal brain development and functions. Interest is growing about the implications of folic acid employment in neuropsychiatric disorders.


Review Article

The View Point of Covid-19: Update Information

E Ghazizadeh*; Zahra Naseri

At the end of December 2019, "pneumonia of unknown cause" occurred Later, the specialized cause was identified and coined as Severe Respiratory Disorders Coronavirus 2 (SARS-CoV-2), and the disease was named "Coronavirus Disease 2019" (COVID-19).


Short Report

Electrocardiographic Variants of Ventricular Predominance in Arrhythmogenic Cardiomyopathy

Stefan Peters*

Desmoglein-2 and Desmocollin-2 mutations cause different types of arrhythmogenic cardiomyopathy either dominant right, biventricular or dominant left forms. These two mutations present with myocardial cell necrosis and calcification [1,2].


Short Commentary

Rationale for Living Donor Organ Transplantation

Angelika C Gruessner; Rainer WG Gruessner*

The use of Living Donors (LDs) for the purpose of solid organ transplantation has raised many questions and concerns from the very infancy of this field and have continued over time.


Research Article

The Effective Factors on the Adherence to Drugs Treatment Behaviors in Multiple Sclerosis Patients Based on Theory Planned Behavior

Sara Hamtaeigashti; Mohsen Shamsi*; Mohammad Ali Sahraian; Raheleh Soltani; Amir Almasi-Hashiani

In Multiple Sclerosis (MS), non-adherence is related to suboptimal response to treatment, including disease relapses and the need for more expensive healthcare. The aim of this study was to identify predictors related to treatment adherence drugs in Iranian MS patients.


Research Article

Formulation and Evaluation of Lozenges Containing Freeze Dried Aqueous Extract of Mangifera indica for Management of Diabetes Mellitus

Udem Ngozi Dorathy*; Adikwu Michael Umale

This study focused on the formulation of freeze dried Mangifera indica. (MI) lozenges dosage form, which enables proper dosing of MI for patients that are unable to swallow solid drugs. Soft lozenges containing freeze dried aqueous extract of MI were prepared by melting Polyethylene glycol 1000(PEG 1000) to 70oC and gradually addition of MI with stirring after cooling.


Research Article

Assessment of Surgical Treatment Results of Adult Traumatic Femoral Neck Fracture

Javad Khajemozafari*; Karim Pisoudeh; Mohammad Reza Sarshar; Mohammad Bagher Sohrabi

Femoral Neck Fracture (FNF) is one of the most common that, causing problems and complications for patients. The purpose of the present study is to investigate surgical treatment results of traumatic femoral neck fracture in adults under 60 years.


Research Article

The Effects of Surgical Lipedema Therapy on Psychological Variables in Younger Patients between 18 and 35 Years

Sophie Florine Arndt; Erich Kasten*; Bernd Klesper

Lipedema is a chronic inflammatory fat distribution disorder that largely affects women. This article addresses the effects of surgical lipedema therapy to changes in the constructs of self-esteem, quality of life, body image, and the development of depressive symptoms.


Research Article

Targeted Screening for Undiagnosed Chronic Kidney Disease among Asymptomatic Immediate Family Members of Chronic Kidney Disease Patients: Experience from a Teaching Hospital in South Eastern Nigeria

Bartholomew C Ozuemba; Chidiebele M Ezeude*

Chronic Kidney Disease (CKD) is a worldwide epidemic that is associated with a huge morbidity, mortality and high healthcare cost. In Nigeria, the number of patients with CKD progressing to End Stage Renal Disease (ESRD) is increasing.


Case Series

Dermoscopy in the Diagnosis of Darier's Disease: A Precise Approach

Kaoutar Mejjati*; Zakia Douhi; Souhaila El Yaagoubi; Meryem Soughi; Sara Elloudi; Hanane Baybay; Layla Tahiri EL Ousrouti; Fatima Zahra Mernissi

Darier's disease, a rare genetic condition with autosomal transmission that alters keratinization, clinically manifests as pruritic keratotic papules, mainly localized on seborrheic areas. Due to the similarity in presentation with other pathologies, dermoscopy plays a crucial role in diagnostic orientation.


Clinical Image

Renal Biopsy in Monoclonal Gammopathies

Giovanni D'Arena1*; Giuseppe Gigliotti

The association between monoclonal gammopathies and kidney damage is commonly seen. In Multiple Myeloma (MM) the renal involvement is a sign of active disease to be treated. In addition, a clinical condition called "monoclonal gammopathy of renal significance" has been proposed in 2012 to describe hematological conditions producing a monoclonal immunoglobulin associated with kidney injury outside of MM and Monoclonal Gammopathy of Undetermined Significance (MGUS).


Case Report

Methodology Based on the Continuous Wavelet Transform for Estimation of the Drop Jump Gesture

Mayorga Laura*; Sierra Alexander; Rodríguez Luis

One of the main objectives of sports biomechanics is the improvement of sports performance. The Drop Jump (DJ) is a vertical jump that seeks to evaluate reactive strength capacity, which can also be expressed as the ability to perform the muscle Stretch Shortening Cycle (SSC) quickly [1].


Research Article

Social Determinants of Health Services Utilization Among Patient with Chronic Diseases Based on the China Health and Retirement Longitudinal Survey

Cheng Cong; Xiao Lei; Yang Jian; Hu Qian; Yang Yuan; Zhang Fan*

In a word, the published studies are about health services among different population groups. Moreover, most of these studies focused on the relationship between medical insurance and health services, without utilizing the latest data and large sample sizes.


Research Article

Mumps is Transmitted by Droplets

Siniša Franjić*

Mumps is an acute, contagious viral disease with characteristic enlargement and pain of the salivary glands, most often the parotid. The diagnosis is usually made on the basis of the clinical picture, and the treatment is supportive.


Mini Review

Virtual Reality in Mental Health Interventions: A Mini-Review

Jose Ferrer Costa*

The escalating incidence of mental health disorders calls for innovative therapeutic interventions. Virtual Reality (VR) has emerged as a significant augmentation to traditional therapeutic strategies, including cognitive-behavioral therapy and exposure therapy.


Short Commentary

Adherence to Diet Advice Accelerates Weight Loss After 25 Days

Brian Wansink*

To determine the relationship between the number of days of adherence to weight loss advice and actual weight loss. Weight loss tips were randomly assigned within broad categories to participants. Number of days of adherence and weight loss were then recorded. Tips were distributed through a popular weight loss related website.


Case Report

Myalgia and Muscle Weakness Caused by Fish Allergy: A Case Report

Abdelkarim Mohamed; Obada Adel Alsakaji; Muad Abdi Hassan*; Bassem Al Hariri

While being considered part of a healthy diet, consuming fish can induce an allergic response in susceptible individuals, and its subsequent manifestations can range from simple to severe. These manifestations are usually mediated by the activation of mast cells and the release of their mediators.


Case Report

Exploring Dens Invaginatus Types I and II: Diagnosis, Challenges, and Solutions - A Case Report

Hajer Zaghdoudi*; Amira Kikly; Nabiha Douki

Dens invaginatus is a common malformation of maxillary lateral incisors with varying anatomical features that impose challenges to diagnosis and treatment. It is considered a real clinical entity which, even if the tooth is clinically healthy, it can cause pulpal damages that can progress silently and lead to necrosis and its complications.


Research Article

Predictors of Intern Pharmacists Job Satisfaction in Federal Teaching Hospitals in Southeast Nigeria

Eruchalu CJ; Ogbonna BO*; Okafor CI; Onodugo C; Ogbonna JC; Okpi O; Nnamani NR; Okezie S; Ani AC; Agu CM

Job satisfaction is a quality assessment standard measure used in evaluation of employers output and outcomes. Increase in job satisfaction correlates positively with employees output. This study assessed the predictors of intern pharmacists job satisfaction ina tertiary hospital in southeast Nigeria.


Research Article

Evaluation of Community Pharmacist-Based Differentiated Care in HIV/AIDS Management Services in Nigeria from 1980 to 2022: A Narrative Review

Ighorodje E Austine; Daniel U Eze; Victor U Chigozie; Nduka O Sunday; Ogbonna O Brian*

The World Health Organization promotion of community pharmacist-based global strategy to increase access to ART prompted the differentiated care model to meet the target of HIV/AIDS while maintaining quality of care. Published literature has highlights of the involvement with sparse information on the community pharmacists in Rivers State.


Research Article

Comparison of Honey Wax and Olive Oil with 1% Silver Sulfadiazine Dressing on Pain and Wound Healing in Burn

Arezou Karampourian; Javad Feradmal; Roya Amini*; Shirin Moradkhani; Mohammad Yousef Alikhani; Rasoul Salimi; Nahid Mohammadi

Burn is painful, and burn wound healing is a prolonged process. This study aimed to compare the effects of Honey Wax and Olive oil with 1% Silver Sulfadiazine (SSD) dressing on burn wound pain attenuation and healing. Patients with two burn wounds were randomly divided into two groups. One group was dressed with honey wax and olive oil (intervention) and another wound was dressed with SSD (control).


Research Article

Practice, Risk Perception, and Correlates of Self-Medication Among Pregnant Women in Awka

Maduka Anthony; Daniel U Eze; Victor U Chigozie; Ogbonna O Brian*

Despite global discouragement of the practice of self-medication in pregnancy, available data showed that the practice still thrives in many parts of the world, especially the developing nations. Despite the major associated risk of potential harm to the mother and her fetus, self-mediation is believed to be a major driving force behind the increasing burden of anti-microbial resistance.


Research Article

Community Pharmacies, Extent of Services, and Preparedness for Primary Health Care Policy Implementation in Nigeria from 1980 to 2022: A Narrative Review

Mbanefo Maureen O; Daniel U Eze; Osigwe C Clementina; Nnamani Monica; Victor U Chigozie; Ogbonna Brian O*

To attain the goal of universal health coverage it is imperative to effectively utilize all healthcare resources and personnel. However, a significant obstacle to achieving this objective is the lack of comprehensive wholistic up to date information on primary healthcare services and the extent to which community pharmacies participation.

Research Article

The Portrayal of Health Disparities in New Jersey's Local Newspapers: A Text Mining Approach

Mumtahina Obaid; Rifat Afrin*; Ahasan Harun; Gayle Prybutok; Victor R Prybutok

Health disparity ensues when racial and ethnic minorities experience limitations in their ability to access health services, resulting in poor health outcomes. The extent to which the health disparity issue is covered in the news impacts how individuals perceive the severity of the issue and individuals' attitudes toward the issue.


Review Article

Transcranial Magnetic Stimulation (TMS) and Transcranial Direct Current Stimulation (TDCS) in Autism Spectrum Disorder

Leonardo Massoni*

Autism spectrum disorder (ASD) is a neurodevelopmental disease characterized by deficits in social communication and the presence of restricted, repetitive behaviors or interests, as well as difficulties in emotional regulation. To date, pharmacological approaches are essentially limited to some drugs, such as aripiprazole and risperidone.


Research Article

Comparison of Humor Style Preferences Between Successfully Recovering Individuals and Newcomers Participating in 12-Step Recovery Programs

Benjamin Canha*

Humor has long been associated with potential benefits on physical and psychological health and well-being [1]. Identified and developed a tool to measure various functions, forms or styles of humor with either beneficial, adaptive expression or in detrimental, maladaptive operations.


Research Article

Tripterygium Wilfordii Reduces the Inflammatory Response in Transplant Vasculopathy

Qimin Wang; Yanqing Su; Yang Ye; Yao Lu*

Transplant vasculopathy (TV) is the most challenging threat during organ transplantation. The pathological induction of TV results from vascular endothelial cell injury. This study established the in vitro model of TV and investigated the attenuating effect of triptolide (TPL) on TV through multiple in vitro and in vivo assays.


Research Article

Effectiveness of Postnatal Home Visits in Reducing Fatigue Among Mothers with Unplanned Pregnancies

Norikazu Watanabe*; Mika Fukase; Seiji Tsutsumi; Akiko Sugiyama; Keiko Yamanouchi; Satoru Nagase

This study identified the risk factors for fatigue in child-rearing recognizable in early pregnancy and evaluated the effects of postnatal home visits on parenting fatigue. Data from 348 mothers who delivered live infants during January–March 2013 in Japan were collected retrospectively.


Review Article

Postpartum Uterine Diseases; Diagnostic Approaches and Management in Farm Animals: A Review

Natinael Dawit Kalacho*

Postpartum uterine infections results from uterine contamination with bacteria during parturition. The postpartum environment of the uterine lumen supports the growth of a variety of aerobic and anaerobic bacteria. There are a number of risk factors for post-partum uterine disease in dairy cattle; cows having dystocia, retained placenta, twins or stillbirths and various metabolic disorders.


Review Article

Are Freshwater Sources Safe for the Health of Humans and Domestic Animals in Terms of Deadly Trematodiases?

Shanti Lal Choubisa*; Pallavi Choubisa

There are many types of lentic and lotic freshwater sources on earth, such as puddles, ponds, rivers, springs, dams, lakes, etc. and many of them are found near human settlements. But most of the people are not known and aware of these freshwater sources how safe and dangerous they can be.


Research Article

Antioxidant and Anti-Inflammatory Activity of Fractionated Artemia Urmiana Extract in Human Peripheral Blood Neutrophils System

Abdolkhalegh Deezagi*; Parisa Shahram

Marine organisms are great resources for discovering bioactive compounds with new antioxidant properties. The aim of this work was to purify and isolate the protein fractions of Artemia urmiana and to evaluate antioxidant activities of them on human peripheral blood neutrophils response.


Review Article

Cognitive Behavior Therapy (CBT) for those in Early Addiction Recovery

Benjamin Canha*

The honesty exercise is a one-hour-long CBT sessions was designed specifically to treat addictive disorders that focus on the first three steps of the 12 Steps adapted from Alcoholics Anonymous (AA). We admitted we were powerless over alcohol-that our lives had become unmanageable. This review article describes step by step instructions for confronting denial in a new and powerful way using CBT principles. The Honesty Exercise and cartoons [2] were created by the author.


Review Article

A New Hope? Combination Immunotherapy for Microsatellite Stable Colorectal Cancer

Qian Xu; Caiyan Jia; Dan Yi; Fanming Kong; Yingjie Jia*

Colorectal cancer (CRC) is one of the three most common malignancies globally while the mortality ranks second. Currently immunotherapy, like therapeutic monoclonal antibodies targeting immune checkpoints, have been found to have obvious benefit for patients who are DNA mismatch repair deficiency (dMMR)/high microsatellite instability (MSI-H) CRC.