It has been reported that dysregulated Transthyretin (TTR) transcript and decreased protein expression during fibrotic progression. Therefore, TTR gene is expected to become a target for hepatic fibrosis monitoring. The study aims to prepare and evaluate a fluorine-18-labeled transthyretin siRNA molecular probe targeting TTR mRNA for PET imaging of liver fibrosis preclinically.

Biliary obstruction arises from various biliary diseases, and its alleviation can minimize obstructive jaundice and reduce risks of acute suppurative obstructive cholangitis. Bio-3D-printed biliary stents, building upon conventional designs, incorporate cells and drug-delivery capabilities to promote biliary repair and lower recurrence rates.

In general, people levied every kind of inconveniences to population growth. The United Nations’ 17 Sustainable Development Goals (SDGs) aim to achieve decent lives for all on a healthy planet by 2030. As things stand, most of them are likely to be missed.

Osteoarthritis (OA) is considered the most common musculoskeletal disease, affecting more than 240 million people worldwide. Most patients develop OA in the lower joints, such as knee or hip. Nearly 30% of individuals over the age of 45 show radiographic evidence of knee (Gonarthrosis) and hip (Coxarthrosis) OA.

Seventy-six patients diagnosed with Coronary Heart Disease (CHD) and Type 2 Diabetes Mellitus (T2DM) were included in this study conducted at the Department of Cardiology, First Affiliated Hospital of Kunming Medical University, between January 2022 and August 2023. The patients were stratified ...

Hypertension is highly prevalent and constitutes a significant risk factor for Target Organ Damage (TOD), such as cardiac and renal lesions, thereby increasing morbidity and mortality. However, the magnitude of these complications among hospitalized patients remains underexplored in Brazil.

The current study demonstrates how spray coating can be used as a rapid and scalable technique to fabricate CNF-MMT nanocomposites with improved barrier properties, particularly in terms of water vapor permeability.

Rapid progress in vaccine development was prompted by the unprecedented global health challenge posed by the emergence of the novel coronavirus disease (COVID-19) caused by SARS-CoV-2. The current state of COVID-19 vaccines.

Online career orientation tools have become increasingly popular to aid medical students navigate speciality selection during the match process. However, there is a scarcity of publications regarding the impact.

Vitamin B12 (cobalamin) deficiency is a common yet underdiagnosed condition with heterogeneous clinical presentations and diverse etiologies. Its management requires an individualized approach that considers not only the biochemical severity.