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Latest Articles

Research Article

Pan-Cancer Analysis of HSP90AB1 Prognosis and Immune Effects: A Potential Target for Survival and Immunotherapy

Shichao Liu*; Xiaolan Shao; Renyi Geng; Jinxin Wang

Emerging evidence reveals an important role of Heat shock protein 90 kDAα, Class B, Member 1 (HSP90AB1) in cancer initiation, development, and progression, but no pan-cancer analysis of HSP90AB1 has been performed.

Research Article

SLC39A10 Expression is Associated with the Prognosis of Hepatocellular Carcinoma and the Tumor Immune Microenvironment

Siqi Li; Shichao Liu*

Zinc is essential for cellular processes and has been implicated in the development of various malignancies. The protein SLC39A10, which facilitates zinc transport, is suspected to contribute to tumor growth in multiple types of cancer.

Research Article

Investigating the Causal Relationship Between Rheumatoid Arthritis and Neuroimaging Features Using Mendelian Randomization

Kai Wang; Dehai Xian; Kaiwen Yang*

Rheumatoid Arthritis (RA) primarily affects joints but can also impact the brain. Research suggests RA may alter brain function through inflammation, but the causal link remains unclear. This study utilizes Mendelian Randomization (MR) to explore the causal relationship between RA and various neuroimaging features.

Case Report

Severe Encephalitis Complicated by Intracranial Hypertension and Incipient Uncal Herniation in a 41-Year-Old Woman: A Case Report

Celeste Bonomi D'Imperio; Rafael Suárez Del Villar Carrero*

We present a case of a 41-year-old female who developed encephalitis complicated by increased intracranial pressure (HTIC) and incipient uncal herniation. The patient presented with fever, headache, and progressive loss of consciousness.

Case Report

Biliary Atresia Polysplenic Malformation Syndrome: Case Report

Ibtissam El Ouali*; Kawtar Imrani; Kenza Berrada; Hiba Zahi; Nabil Moatassim Billah; Ittimade Nassar

Biliary atresia is a rare disease of unknown etiology characterized by an obstruction of biliary ducts occurring during the prenatal period due to progressive fibrosis of extrahepatic biliary ducts.

Clinical Image

A Complicated Form of Penetrating Aortic Ulcer Revealed by Hemoptysis

Ibtissam El Ouali*; Kenza Berrada; Soumiya El Graini; Omar El Oufir

Penetrating Aortic Ulcer (PAU), first described in 1934, consists of an ulcerating atherosclerotic lesion located in the aortic wall that penetrates the intima and progresses through the internal elastic lamina into the media causing formation of hematoma within it.

Short Commentary

Risk Management in Dental Practice: Challenges and Strategies for Enhancing Patient Safety

Ashish Pandey*

Risk management in dental practice has evolved as a critical component of clinical care, ensuring the safety of both patients and practitioners. As dental treatments become more complex and technologies advance, understanding the multifaceted risks associated with dental procedures is paramount.

Case Report

Infantile Capillary Hemangioma in 3-Month-Old Girl: A Case Report

Arun Naphe Khatri*

Infantile hemangiomas are common vascular tumors occurring in infancy and early childhood, with a prevalence of approximately 5-10% among infants. These hemangiomas develop due to an abnormal proliferation of capillaries, which are densely packed and lack open lumens.

Research Article

Investigating Gene Expression Profiles in Interstitial Cystitis (IC): Unraveling Molecular Mechanisms and Potential Therapeutic Targets

Adishi Ranjan*

Interstitial Cystitis (IC), also known as painful bladder syndrome, is a chronic disease that significantly reduces the quality of life for patients. Symptoms include pelvic pain, increased urinary frequency, urgency, and inflammation of the mucosa and interstitial layers of the bladder [1].

Case Report

Pulmonary Veno Occlusive Disease - A Rare Cause of Pulmonary Hypertension: A Case Report

Perera MNSK*; Gunapala A

Pulmonary veno occlusive disease is a rare cause of pulmonary hypertension which has a relentlessly progressive course with high morbidity and mortality. Because of rarity of the disease, management options are also not well established.