Recto-ureteral fistulas are an unusual disease, mainly associated with prostate cancer, either secondary to radical prostatectomy or radiotherapy, with an estimated incidence of <2% of cases. Our team presents an even more exceptional case, due to a recto-prostatic-penileal fistula secondary to a perforated rectal neoplasm.

A 53-year-old man presented with abdominal distension and vomiting lasting three months. Further examination in the ward confirmed a diagnosis of antral malignant tumor with pyloric obstruction. The patient was then transferred to surgical oncology.

The aim is to formulate freeze dried Vernonia Amygdalina (VA) lozenges dosage form. VA lozenges combined with Glibenclamide and Metformin standard anti-diabetic effect will also be studied. This will enable proper dosing of VA for patients that are unable to swallow solid drugs.

Long Covid is an emerging public health public problem; the ligering symptoms after Covid-19 infection can last weeks to months. At present, no pharmacologic agent has been know that effectively reduces or abolishes the symptoms of long COVID.

Chronic diseases, such as Cardiovascular Diseases (CVD), diabetes, Rheumatoid Arthritis (RA), and Chronic Kidney Disease (CKD), are among the most pressing global health challenges of the 21st century [1]. These conditions account for a significant portion of morbidity and mortality worldwide, placing an immense burden on healthcare systems and societies [2].